|Last Recorded Age||Unknown|
|Voice actor||Swoosie Kurtz|
Elizabeth "Betty" Smith is Stan's mother and Jack Smith's ex-wife. She has had many boyfriends after her husband Jack left the family, but they were all kidnapped and taken to an island by Stan who was afraid they would all hurt her just like his father did. Betty marries Hercules in "Oedipal Panties" who was almost kidnapped by Stan. When Francine is telling Roger about Stan's childhood he has a flashback of his father Jack leaving him and his mother Betty. She falls in love with, and later marries, a Greek butcher named Hercules.
She appears in a non-speaking cameo in "Shallow Vows".
Hercules dies in "American Stepdad" and she reveals to Stan and Francine that the funeral has left her broke. They invite her to come live with them and kick Roger out of the attic to make room for her. But when Stan arrives home later, he finds that Jeff Fischer is moving Roger's stuff back upstairs and he and Betty reveal that they got married under Roger's persona of Tom Yabo. At first, Stan believes that Roger is only trying to get back into his attic, but they bond just as Betty and Roger head to Niagara Falls for a honeymoon. Stan finds evidence that suggests that Roger plans of killing his mother, but when he arrives at the falls to stop him Betty reveals that she planned on killing Roger for the life insurance. When she tries to push Roger over the falls, they both slip and Stan grabs both but is unable to save the pair. In order to preserve his relationship with Stan, Roger sacrifices himself but turns up leading a tour group at the falls. Betty moves to Paris, France on Tom Yabo's life insurance but is disappointed when she stops in a theater to see Fast and the Furious 7 only to discover she missed many of the gay sex scenes.
Betty also appears in the cast of "Blood Crieth Unto Heaven".