This episode involves a crossover plot of a hurricane affecting all three current Seth MacFarlane shows including The Cleveland Show in "The Hurricane" and Family Guy in "Seahorse Sea Shell Party". It is a parody of a stunt used by NBC on November 9, 1991 alternately called Night of the Hurricane and Hurricane Saturday involving a hurricane simultaneously affecting the sitcoms The Golden Girls, Empty Nest, and Nurses. It was first brought up when MacFarlane originally announced at the 2010 Comic-Con that the three fathers of his shows would be in the same scene at some point. The stand-off at the end of the episode with Stan Smith and Cleveland Brown having their guns on each other and Peter Griffin having his guns on them is the scene MacFarlane was talking about.
The three episodes of "The Hurricane", "Hurricane!", "Seahorse Seashell Party" aired about a month after Hurricane Irene, which affected both Virginia and Rhode Island.
This episode was originally set to air May 1, 2011, but was pulled in light of a tornado in the South.
This is the first official American Dad! episode to cross over with Family Guy. The reverse occurred twice in the latter, first in the episode "Lois Kills Stewie", although that was a computer simulation, and the second being "Excellence in Broadcasting". It was originally accepted that both shows were separate entities as was evidenced by the fact that Klaus was wearing Family Guy merchandise in "The Return of the Bling", and Stan was watching Brian become a Republican on his television set in the FG episode "Excellence in Broadcasting".
Klaus attempts to get Stan's spirits up by mentioning most of Nicolas Cage's career and claiming his best movie was National Treasure 2: Book of Secrets.
Cleveland and Peter each have three lines for their crossover appearances at the end of this episode.
Roger is apparently dating a human girl in this episode, when it is unknown of what his sexuality is, and the fact that he never really dated a human girl before.
When Stan steps out of his house, he sees Cleveland's neighbor Lester Krinklesac's home across the street as evidenced by the ramp for his wife, Kendra. Cleveland and Peter's houses are next door to either side.