Here is a list of known pop & rock music used in episodes of American Dad!, both pre-recorded and sung by the cast as Musical Numbers.
- 2 LIVE CREW – "Me So Horny": "Stanny_Slickers_2:_The_Legend_of_Ollie's_Gold"
- ABC – "The Look Of Love": "It's Good to Be the Queen"
- AC/DC - "If You Want Blood": "Cock of the Sleepwalk"
- Ace of Base – "The Sign": "Great Space Roaster"
- Andrea True Connection – "More, More, More": "Meter Made"
- August Burns Red – "Carol of the Bells": "For Whom the Sleigh Bell Tolls"
- Average White Band - "Pick Up The Pieces": "Stanny-Boy and Frantastic"
- B-52s - "Legal Tender": "Faking Bad"
- Bachman–Turner Overdrive - "Takin' Care of Business": "The Boring Identity"
- Bananarama -- "Venus": "Moon Over Isla Island"
- The Bangles – "Walk Like an Egyptian": "Helping Handis"
- Billie Holiday - "Strange Fruit": "Blood Crieth Unto Heaven"
- Black Eyed Peas – "I Gotta Feeling": "Best Little Horror House in Langley Falls"
- Black Eyed Peas – "Let's Get It Started": "Spring Break-Up" and "White Rice"
- Black Eyed Peas – "Rock That Body": "Best Little Horror House in Langley Falls"
- Bobby Fuller Four – "I Fought the Law": "The People vs. Martin Sugar"
- Booker T. & The MG's – "Green Onions": "Bar Mitzvah Hustle"
- Boots Randolph – "Yackety Sax" - "May the Best Stan Win & "The Scarlett Getter"
- The BPA, featuring Iggy Pop – "He's Frank (Slight Return)": "Son of Stan"
- Brian Tochi - "Daichee": "Home Adrone"
- Cake - "Mustache Man (Wasted)": "She Swill Survive"
- Carl Broemel - "Carried Away": "Stan's Best Friend"
- Carl Orff – "O Fortuna": "A Smith In The Hand"
- Carly Rae Jepsen - "Call Me Maybe": "Introducing the Naughty Stewardesses"
- C+C Music Factory (Presenting Freedom Williams) – "Gonna Make You Sweat (Everybody Dance Now)": "When a Stan Loves a Woman"
- Cheryl Lynn – "Got To Be Real": "Best Little Horror House in Langley Falls"
- Chicago – "Colour My World": "Brains, Brains and Automobiles"
- The Clash – "Rock The Casbah": "Stan of Arabia: Part 1"
- Creedence Clearwater Revival – "Fortunate Son": "In Country...Club
- Christopher Cross - "Sailing": "Stan of Arabia: Part 2"
- Coolio - "Gangsta's Paradise": "Jenny Fromdabloc"
- Crowded House – "Don't Dream It's Over": "Bullocks To Stan"
- Cyndi Lauper – "The Goonies 'R' Good Enough": "May the Best Stan Win"
- Cypress Hill – "Hand On The Pump": "Cops and Roger"
- Cypress Hill - "Rock Superstar": "The Boring Identity"
- Dan Navarro - "Cilantro's El Perro": "Roy Rogers McFreely"
- Dawes - "Just Beneath the Surface": "Independent Movie"
- Dean Martin – "Ain't That A Kick In The Head": "Meter Made"
- Def Leppard – "Pour Some Sugar On Me": "Helping Handis"
- Delta Spirit - "California": "Independent Movie"
- Deniece Williams – "Let's Hear It For The Boy": "The American Dad After School Special"
- Diana Ross – "I'm Coming Out": "Man in the Moonbounce"
- Dolly Parton – "9 to 5": "Bush Comes to Dinner
- Dolly Parton – "Jolene": "Bush Comes to Dinner
- Earth, Wind & Fire – "September": "Finances With Wolves"
- Elastica – "Connection": "Not Particularly Desperate Housewives"
- Electric Light Orchestra – "Mr Blue Sky": "Fartbreak Hotel"
- The English Beat – "Tears Of A Clown": "Tearjerker"
- Eric B. & Rakim – "Know The Ledge": "Don't Look a Smith Horse in the Mouth"
- Etta James - "At Last": "Shallow Vows"
- Fascinoma – "I'm Walking This Road Because You Stole My Car (Don't Go)": "Choosy Wives Choose Smith"
- Fun - "We Are Young": "Faking Bad"
- Genesis – "Invisible Touch": "Old Stan in the Mountain"
- Gerry Rafferty - "Baker Street": "Stan of Arabia: Part 1"
- Ginuwine – "My Pony": "I Am the Walrus"
- Glenn Miller – "Moonlight Becomes You": "Iced, Iced Babies"
- Glenn Miller – "Pennsylvania 6-5000": "The One That Got Away"
- Harry Nilsson – "Everybody's Talkin'": "Irregarding Steve"
- Harry Nilsson - "Best Friend": "American Stepdad"
- Huey Lewis and the News – "Hip to be Square": "The Kidney Stays in the Picture
- INXS – "Never Tear Us Apart": "It's Good to Be the Queen"
- Irene Cara (Fame Soundtrack) – "Out Here On My Own": "Moon Over Isla Island"
- Iris Williams – "I'm Gonna Live 'Til I Die": "Fartbreak Hotel"
- Jackson 5 - "ABC": "Spelling Bee My Baby"
- James Ingram & Michael McDonald - "Ya Mo Be There": "Home Wrecker"
- Jane's Addiction – "Stop": "The Vacation Goo"
- Jefferson Airplane – "White Rabbit": "In Country...Club"
- Johann Sebastian Bach - "Air" (From Suite No. 3 In D Major): "Pulling Double Booty"
- Joe Satriani - "Always With Me, Always With You": "Why Can't We Be Friends?"
- John Cafferty - "Hearts On Fire": "Poltergasm"
- John Denver – "Take Me Home, Country Roads": "American Dream Factory"
- John Farnham –"Thunder In Your Heart": "Son of Stan"
- Salt-N-Pepa -"Push It": "The New CIA"
- Johnny Mathis - "Chances Are": "Finger Lenting Good"
- Journey – "Open Arms": "There Will Be Bad Blood"
- Journey – "Wheel in the Sky": "Stan's Best Friend"
- Journey - "Be Good to Yourself": "Da Flippity Flop"
- Joy Division – "Love Will Tear Us Apart": "Escape from Pearl Bailey"
- Jude Cole - "Back to School": "The Wrestler"
- KC & the Sunshine Band - "That's the Way I Like It": "The Best Christmas Story Never"
- Kenny Loggins – "Footloose": "Four Little Words"
- Kenny Loggins – "Playing With The Boys": "Phantom of the Telethon"
- Kenny Wayne Shepherd - "Spank": "The Missing Kink"
- Kim Mitchell – "Go For Soda": "A.T. The Abusive Terrestrial"
- The Knack – "My Sharona": "Iced, Iced Babies"
- Kool and the Gang - "Jungle Boogie": "A Jones for a Smith"
- LMFAO - "Shots": "Can I Be Frank (With You)"
- Laura Branigan – "Gloria": "Of Ice and Men"
- Little River Band – "Cool Change": "Frannie 911"
- Looper – "Mondo '77": "All About Steve"
- Loose Fur - "The Ruling Class": "Stan's Best Friend"
- Los del Rio - "Macarena": "The Kidney Stays in the Picture"
- Lou Bega - "Mambo No. 5": "Daddy Queerest"
- Louis Armstrong – "Nobody Knows The Trouble I've Seen": "White Rice"
- Loverboy - "The Kid is Hot Tonight": "Office Spaceman"
- LSG - "My Body": "Ricky Spanish"
- Marc Anthony - "I Need To Know": "Wife Insurance"
- Marvin Gaye – "Let's Get It On": "The People vs. Martin Sugar"
- Maurice Chevalier – "Hello Beautiful": "Four Little Words"
- MGMT – "Electric Feel": "Son of Stan"
- Michael Bolton - "How Am I Supposed to Live Without You": "Live and Let Fry"
- Michael Jackson - "Billie Jean": "She Swill Survive"
- Mickey Avalon – "My Dick": "License to Till"
- Midnight Oil - "Beds are Burning": "The Full Cognitive Redaction of Avery Bullock by the Coward Stan Smith"
- Missy Elliot - "Get Ur Freak On": "Steve and Snot's Test-Tubular Adventure"
- MO7S – "Tesla (Tim Wright Remix)": "Gorillas in the Mist"
- Maurice Chevalier - "Thank Heaven For Little Girls": "Steve and Snot's Test-Tubular Adventure"
- My Morning Jacket – "I’m Amazed": "My Morning Straitjacket"
- My Morning Jacket – "Remnants": "My Morning Straitjacket"
- My Morning Jacket – "Touch Me I’m Going To Scream Pt. 2": "My Morning Straitjacket"
- My Morning Jacket – "Wordless Chorus": "My Morning Straitjacket"
- My Morning Jacket – "Slow, Slow Tune": "Gorillas in the Mist"
- New Edition - "Cool It Now": "Can I Be Frank (With You)"
- Night Ranger – "Sister Christian": "Joint Custody" and "Dope & Faith"
- Oingo Boingo – "Little Girls": "Bullocks To Stan"
- Oingo Boingo – "Weird Science": "Stan's Best Friend"
- Olivia Newton-John & Electric Light Orchestra – "Xanadu": "The Vacation Goo"
- Parliament – "Flash Light": "Phantom of the Telethon"
- Paul Engemann - "Push it to the Limit": "The Adventures of Twill Ongenbone And His Boy Jabari"
- Paula Abdul – "Cold Hearted": "Dr. Klaustus"
- Pet Shop Boys – "West End Girls": "Roger 'n' Me"
- Public Enemy – "911 Is A Joke": "Finances With Wolves"
- Queen - "Bicycle Race": "Jack's Back"
- Queen – "Don't Stop Me Now": "Roger 'n' Me"
- R. Kelly - "I Believe I Can Fly": "Star Trek"
- Rick Derringer - "Real American": "Stanny Tendergrass"
- Rob Base & DJ EZ Rock – "It Takes Two": "G-String Circus"
- Robbie Dupree - "Steal Away": "Crotchwalkers"
- Roxette – "The Look": "Fartbreak Hotel"
- Sade - "No Ordinary Love": "Stan Goes On the Pill"
- Salt-N-Pepa – "Push It": "White Rice"
- Sam Cooke – "Good Times": "A Piñata Named Desire"
- Samuel Barber - "Adagio for Strings": "In Country...Club"
- Sarah Vaughan – "I'm Gonna Live Till I Die": "Fartbreak Hotel"
- Simple Minds – "Don't You (Forget About Me)": "Failure is not a Factory-Installed Option"
- Sinead O'Connor - "Nothing Compares 2 U": "Finger Lenting Good"
- Sisqó - "Thong Song": "Max Jets"
- Soulja Boy Tell'em – "Turn My Swag On": "Less Money, Mo' Problems"
- Stan Bush - "The Touch": "Cops and Roger"
- Sté ÉLéCtro 2 – "Street Fabulous": "Stanny-Boy and Frantastic"
- Sugar Ray – "Fly": "Spring Break-Up"
- Ted Nugent – "Cat Scratch Fever": "Stannie Get Your Gun" (NGA Land)
- Temptations - "My Girl": "Steve and Snot's Test-Tubular Adventure"
- Third Eye Blind - "Jumper": "The Scarlett Getter"
- Toto – "Africa": "Bullocks To Stan" and "Camp Refoogee"
- Train – "Drops of Jupiter": "Bully for Steve"
- Trio - "Da Da Da": "Buck, Wild"
- The Turtles – "Happy Together": "Ricky Spanish"
- Van McCoy – "The Hustle": "The Best Christmas Story Never"
- Wax Fang - "Majestic": "Lost in Space"
- Whitesnake – "Here I Go Again": "Dungeons and Wagons"
- Whitney Houston – "I Will Always Love You": "Lincoln Lover"
- Wings - "Silly Love Songs": "Star Trek"