The Walgreen Company (Walgreens), founded in Chicago, IL in 1901, is the largest drug retailing chain in the United States.

Francine, Hayley and Roger shop at Walgreens in "Blonde Ambition", dodging an activist collecting signatures on the way in. But when Hayley stops to chat and discovers her cause is bogus, becomes angry that her success in collecting signatures is due to her being a blonde.

While Francine shops, she notes that she is tired of Walgreens and is ready to move up to a Duane Reade, another drug store branch also owned by Walgreens, and when a passing shopper raves about Duane Reade, follows him to learn more.

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